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Cell-type specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
DARPP-32 is a dual function protein kinase/phosphatase inhibitor which plays a vital role in striatal signaling. The phosphorylation of DARPP-32 at T34 is essential for mediating the effects of both psychostimulant and antipsychotic drugs; however these drugs are known to have opposing behavioral an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737705/ https://ncbi.nlm.nih.gov/pubmed/18622401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2153 |
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