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DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

Mitotic catastrophe is the response of mammalian cells to mitotic DNA damage. It produces tetraploid cells with a range of different nuclear morphologies from binucleated to multimicronucleated. In response to DNA damage, checkpoints are activated to delay cell cycle progression and to coordinate re...

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Autors principals: Huang, Xingxu, Tran, Thanh, Zhang, Lingna, Hatcher, Rashieda, Zhang, Pumin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC545827/
https://ncbi.nlm.nih.gov/pubmed/15650047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409130102
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