Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling

Chronic metabolic inflammation in adipose tissue plays an important role in the development of obesity-associated diseases. Our previous study indicated that total saponins of Panax japonicus (SPJ) rhizoma and Chikusetsu saponin V, one main component of SPJ, could exert the anti-oxidative and anti-i...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Yuan, Chengfu, Liu, Chaoqi, Wang, Ting, He, Yumin, Zhou, Zhiyong, Dun, Yaoyan, Zhao, Haixia, Ren, Dongming, Wang, Junjie, Zhang, Changcheng, Yuan, Ding
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458186/
https://ncbi.nlm.nih.gov/pubmed/28415686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16052
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