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Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9
Toll-like receptors encounter a diversity of degradation products in endosomes. TLR7 and TLR8 have been shown to be activated by RNA degradation products. Here we show that although TLR9 requires single-stranded DNA longer than 20 nucleotides for a robust response, TLR9 activation is augmented by Cp...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458134/ https://ncbi.nlm.nih.gov/pubmed/28530246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15363 |
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