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Histone modifications defining active genes persist after transcriptional and mitotic inactivation

We examined various histone modifications across the promoter and the coding regions of constitutively active hepatic genes in G0/G1-enriched, mitotically arrested and α-amanitin-blocked cells. Gene activation correlated with localized histone hyperacetylation, H3-K4 tri- or dimethylation and H3-K79...

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Autors principals: Kouskouti, Antigone, Talianidis, Iannis
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC545808/
https://ncbi.nlm.nih.gov/pubmed/15616580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600516
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