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Histone modifications defining active genes persist after transcriptional and mitotic inactivation
We examined various histone modifications across the promoter and the coding regions of constitutively active hepatic genes in G0/G1-enriched, mitotically arrested and α-amanitin-blocked cells. Gene activation correlated with localized histone hyperacetylation, H3-K4 tri- or dimethylation and H3-K79...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545808/ https://ncbi.nlm.nih.gov/pubmed/15616580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600516 |
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