MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model

We introduce a method (MONKEY) to identify conserved transcription-factor binding sites in multispecies alignments. MONKEY employs probabilistic models of factor specificity and binding-site evolution, on which basis we compute the likelihood that putative sites are conserved and assign statistical...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Moses, Alan M, Chiang, Derek Y, Pollard, Daniel A, Iyer, Venky N, Eisen, Michael B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545801/
https://ncbi.nlm.nih.gov/pubmed/15575972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-12-r98
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky