The Janus kinases (Jaks)

The Janus kinase (Jak) family is one of ten recognized families of non-receptor tyrosine kinases. Mammals have four members of this family, Jak1, Jak2, Jak3 and Tyrosine kinase 2 (Tyk2). Birds, fish and insects also have Jaks. Each protein has a kinase domain and a catalytically inactive pseudo-kina...

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Bibliographic Details
Main Authors: Yamaoka, Kunihiro, Saharinen, Pipsa, Pesu, Marko, Holt, Vance ET, Silvennoinen, Olli, O'Shea, John J
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Protein Family Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545791/
https://ncbi.nlm.nih.gov/pubmed/15575979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-12-253
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