Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis

The alarmin IL-33 has been described to be upregulated in human and murine viral hepatitis. However, the role of endogenous IL-33 in viral hepatitis remains obscure. We aimed to decipher its function by infecting IL-33-deficient mice (IL-33 KO) and their wild-type (WT) littermates with pathogenic mo...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Carrière, Virginie, Arshad, Muhammad Imran, Le Seyec, Jacques, Lefevre, Benjamin, Farooq, Muhammad, Jan, Aurélien, Manuel, Christelle, Touami-Bernard, Laurence, Lucas-Clerc, Catherine, Genet, Valentine, Gascan, Hugues, Girard, Jean-Philippe, Chalmel, Frédéric, Lamontagne, Lucie, Piquet-Pellorce, Claire, Samson, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457781/
https://ncbi.nlm.nih.gov/pubmed/28607531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1359064
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