Mitochondrial Transfer from Wharton's Jelly Mesenchymal Stem Cell to MERRF Cybrid Reduces Oxidative Stress and Improves Mitochondrial Bioenergetics

Myoclonus epilepsy associated with ragged-red fibers (MERRF) is a maternally inherited mitochondrial disease affecting neuromuscular functions. Mt.8344A>G mutation in mitochondrial DNA (mtDNA) is the most common cause of MERRF syndrome and has been linked to an increase in reactive oxygen species...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chuang, Yao-Chung, Liou, Chia-Wei, Chen, Shang-Der, Wang, Pei-Wen, Chuang, Jiin-Haur, Tiao, Mao-Meng, Hsu, Te-Yao, Lin, Hung-Yu, Lin, Tsu-Kung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457778/
https://ncbi.nlm.nih.gov/pubmed/28607632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5691215
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