ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

BACKGROUND: Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer development and progression. RESULTS: In this study, we ana...

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Publicat a:Clin Epigenetics
Autors principals: Richter, Antje M., Kiehl, Steffen, Köger, Nicole, Breuer, Janina, Stiewe, Thorsten, Dammann, Reinhard H.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457737/
https://ncbi.nlm.nih.gov/pubmed/28588743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0360-4
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