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Combining electron microscopy with single molecule DNA fiber approaches to study DNA replication dynamics

Replication stress is a crucial driver of genomic instability. Understanding the mechanisms of replication stress response is instrumental to improve diagnosis and treatment of human disease. Electron microscopy (EM) is currently the only technique that allows to directly visualize a high number of...

詳細記述

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書誌詳細
出版年:Biophys Chem
主要な著者: Vindigni, Alessandro, Lopes, Massimo
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457720/
https://ncbi.nlm.nih.gov/pubmed/27939387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2016.11.014
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