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Combining electron microscopy with single molecule DNA fiber approaches to study DNA replication dynamics

Replication stress is a crucial driver of genomic instability. Understanding the mechanisms of replication stress response is instrumental to improve diagnosis and treatment of human disease. Electron microscopy (EM) is currently the only technique that allows to directly visualize a high number of...

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Detalhes bibliográficos
Publicado no:Biophys Chem
Main Authors: Vindigni, Alessandro, Lopes, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457720/
https://ncbi.nlm.nih.gov/pubmed/27939387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2016.11.014
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