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An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides

A method for selective and comprehensive enrichment of N-linked glycopeptides was developed to facilitate detection of micro-heterogeneity of N-glycosylation. The method takes advantage of the inherent properties of Fbs1, which functions within the ubiquitin-mediated degradation system to recognize...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Chen, Minyong, Shi, Xiaofeng, Duke, Rebecca M., Ruse, Cristian I., Dai, Nan, Taron, Christopher H., Samuelson, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457524/
https://ncbi.nlm.nih.gov/pubmed/28534482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15487
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