Telomere length correlates with disease severity and inflammation in sickle cell disease

BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...

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書目詳細資料
發表在:Rev Bras Hematol Hemoter
Main Authors: Colella, Marina Pereira, Santana, Barbara A., Conran, Nicola, Tomazini, Vinicius, Costa, Fernando F., Calado, Rodrigo T., Saad, Sara T. Olalla
格式: Artigo
語言:Inglês
出版: Sociedade Brasileira de Hematologia e Hemoterapia 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://ncbi.nlm.nih.gov/pubmed/28577651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2017.02.007
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