Telomere length correlates with disease severity and inflammation in sickle cell disease

BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...

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Dettagli Bibliografici
Pubblicato in:Rev Bras Hematol Hemoter
Autori principali: Colella, Marina Pereira, Santana, Barbara A., Conran, Nicola, Tomazini, Vinicius, Costa, Fernando F., Calado, Rodrigo T., Saad, Sara T. Olalla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Sociedade Brasileira de Hematologia e Hemoterapia 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://ncbi.nlm.nih.gov/pubmed/28577651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2017.02.007
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