Telomere length correlates with disease severity and inflammation in sickle cell disease

BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Rev Bras Hematol Hemoter
Päätekijät: Colella, Marina Pereira, Santana, Barbara A., Conran, Nicola, Tomazini, Vinicius, Costa, Fernando F., Calado, Rodrigo T., Saad, Sara T. Olalla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Sociedade Brasileira de Hematologia e Hemoterapia 2017
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://ncbi.nlm.nih.gov/pubmed/28577651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2017.02.007
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