Telomere length correlates with disease severity and inflammation in sickle cell disease

BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...

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Detalles Bibliográficos
Publicado en:Rev Bras Hematol Hemoter
Main Authors: Colella, Marina Pereira, Santana, Barbara A., Conran, Nicola, Tomazini, Vinicius, Costa, Fernando F., Calado, Rodrigo T., Saad, Sara T. Olalla
Formato: Artigo
Idioma:Inglês
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://ncbi.nlm.nih.gov/pubmed/28577651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2017.02.007
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