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Telomere length correlates with disease severity and inflammation in sickle cell disease
BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...
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| Publicado no: | Rev Bras Hematol Hemoter |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Sociedade Brasileira de Hematologia e Hemoterapia
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457472/ https://ncbi.nlm.nih.gov/pubmed/28577651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bjhh.2017.02.007 |
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