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Screening large-scale association study data: exploiting interactions using random forests

BACKGROUND: Genome-wide association studies for complex diseases will produce genotypes on hundreds of thousands of single nucleotide polymorphisms (SNPs). A logical first approach to dealing with massive numbers of SNPs is to use some test to screen the SNPs, retaining only those that meet some cri...

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Detalhes bibliográficos
Main Authors: Lunetta, Kathryn L, Hayward, L Brooke, Segal, Jonathan, Van Eerdewegh, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545646/
https://ncbi.nlm.nih.gov/pubmed/15588316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-5-32
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