Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection

Fatal outcomes of Ebola virus (EBOV) infections are typically preceded by a ‘sepsis-like’ syndrome and lymphopenia despite T cells being resistant to Ebola infection. The mechanisms that lead to T lymphocytes death remain largely unknown; however, the degree of lymphopenia is highly correlative with...

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Udgivet i:PLoS Pathog
Main Authors: Iampietro, Mathieu, Younan, Patrick, Nishida, Andrew, Dutta, Mukta, Lubaki, Ndongala Michel, Santos, Rodrigo I., Koup, Richard A., Katze, Michael G., Bukreyev, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456411/
https://ncbi.nlm.nih.gov/pubmed/28542576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006397
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