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Ebola Virus Shed Glycoprotein Triggers Differentiation, Infection, and Death of Monocytes Through Toll-Like Receptor 4 Activation

A better understanding of the mechanisms used by Ebola virus to disable the host immune system and spread the infection are of great importance for development of new therapeutic strategies. We demonstrate that treatment of monocytic cells with Ebola virus shed glycoprotein (GP) promotes their diffe...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Iampietro, Mathieu, Santos, Rodrigo I, Lubaki, Ndongala Michel, Bukreyev, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249564/
https://ncbi.nlm.nih.gov/pubmed/30085081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy406
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