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Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY

On the periplasmic side of LacY, two conserved Gly-Gly pairs in helices II and XI (Gly46 and Gly370, respectively) and helices V and VIII (Gly159 and Gly262, respectively) allow close packing of each helix pair in the outward (periplasmic)-closed conformation. Previous studies demonstrate that repla...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Jiang, Xiaoxu, Andersson, Magnus, Chau, Bryan T., Wong, Larissa Y., Villafuerte, Maria Katerina R., Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456280/
https://ncbi.nlm.nih.gov/pubmed/27438891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00666
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