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Structural Similarities between Neuregulin 1–3 Isoforms Determine Their Subcellular Distribution and Signaling Mode in Central Neurons

The Neuregulin (NRG) family of ErbB ligands is comprised of numerous variants originating from the use of different genes, alternative promoters, and splice variants. NRGs have generally been thought to be transported to axons and presynaptic terminals where they signal via ErbB3/4 receptors in para...

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Опубликовано в: :J Neurosci
Главные авторы: Vullhorst, Detlef, Ahmad, Tanveer, Karavanova, Irina, Keating, Carolyn, Buonanno, Andres
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456106/
https://ncbi.nlm.nih.gov/pubmed/28432142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2630-16.2017
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