Dissecting structures and functions of SecA-only protein-conducting channels: ATPase, pore structure, ion channel activity, protein translocation, and interaction with SecYEG/SecDF•YajC

SecA is an essential protein in the major bacterial Sec-dependent translocation pathways. E. coli SecA has 901 aminoacyl residues which form multi-functional domains that interact with various ligands to impart function. In this study, we constructed and purified tethered C-terminal deletion fragmen...

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Publicado en:PLoS One
Autores principales: Hsieh, Ying-hsin, Huang, Ying-ju, Zhang, Hao, Liu, Qian, Lu, Yang, Yang, Hsiuchin, Houghton, John, Jiang, Chun, Sui, Sen-Fang, Tai, Phang C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456053/
https://ncbi.nlm.nih.gov/pubmed/28575061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178307
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