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New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies

PURPOSE: Mantle cell lymphoma is an aggressive B-cell neoplasm that displays heterogeneous outcomes after treatment. In 2003, the Lymphoma/Leukemia Molecular Profiling Project described a powerful biomarker—the proliferation signature—using gene expression in fresh frozen material. Herein, we descri...

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Pubblicato in:J Clin Oncol
Autori principali: Scott, David W., Abrisqueta, Pau, Wright, George W., Slack, Graham W., Mottok, Anja, Villa, Diego, Jares, Pedro, Rauert-Wunderlich, Hilka, Royo, Cristina, Clot, Guillem, Pinyol, Magda, Boyle, Merrill, Chan, Fong Chun, Braziel, Rita M., Chan, Wing C., Weisenburger, Dennis D., Cook, James R., Greiner, Timothy C., Fu, Kai, Ott, German, Delabie, Jan, Smeland, Erlend B., Holte, Harald, Jaffe, Elaine S., Steidl, Christian, Connors, Joseph M., Gascoyne, Randy D., Rosenwald, Andreas, Staudt, Louis M., Campo, Elias, Rimsza, Lisa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455765/
https://ncbi.nlm.nih.gov/pubmed/28291392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.70.7901
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