New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies

PURPOSE: Mantle cell lymphoma is an aggressive B-cell neoplasm that displays heterogeneous outcomes after treatment. In 2003, the Lymphoma/Leukemia Molecular Profiling Project described a powerful biomarker—the proliferation signature—using gene expression in fresh frozen material. Herein, we descri...

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Publicado en:J Clin Oncol
Main Authors: Scott, David W., Abrisqueta, Pau, Wright, George W., Slack, Graham W., Mottok, Anja, Villa, Diego, Jares, Pedro, Rauert-Wunderlich, Hilka, Royo, Cristina, Clot, Guillem, Pinyol, Magda, Boyle, Merrill, Chan, Fong Chun, Braziel, Rita M., Chan, Wing C., Weisenburger, Dennis D., Cook, James R., Greiner, Timothy C., Fu, Kai, Ott, German, Delabie, Jan, Smeland, Erlend B., Holte, Harald, Jaffe, Elaine S., Steidl, Christian, Connors, Joseph M., Gascoyne, Randy D., Rosenwald, Andreas, Staudt, Louis M., Campo, Elias, Rimsza, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2017
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ORIGINAL REPORTS
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455765/
https://ncbi.nlm.nih.gov/pubmed/28291392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.70.7901
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