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Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors

Reversible protein phosphorylation is an essential cellular regulatory mechanism. Many proteins integrate and are modulated by multiple phosphorylation events derived from complex signaling cues. Simultaneous detection and quantification of temporal changes in all of a protein's phosphorylation...

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Main Authors: Ballif, Bryan A., Roux, Philippe P., Gerber, Scott A., MacKeigan, Jeffrey P., Blenis, John, Gygi, Steven P.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC545566/
https://ncbi.nlm.nih.gov/pubmed/15647351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409143102
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