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Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs

Hepatitis B virus (HBV) causes acute and chronic hepatitis and hepatocellular carcinoma. Although a preventive vaccine is available, the therapeutic options for chronically infected patients are limited. It has been shown that RNA interference can prevent HBV gene expression and replication in vivo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Uprichard, Susan L., Boyd, Bryan, Althage, Alana, Chisari, Francis V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545555/
https://ncbi.nlm.nih.gov/pubmed/15640346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409028102
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