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Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs

Hepatitis B virus (HBV) causes acute and chronic hepatitis and hepatocellular carcinoma. Although a preventive vaccine is available, the therapeutic options for chronically infected patients are limited. It has been shown that RNA interference can prevent HBV gene expression and replication in vivo...

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Detalhes bibliográficos
Main Authors: Uprichard, Susan L., Boyd, Bryan, Althage, Alana, Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545555/
https://ncbi.nlm.nih.gov/pubmed/15640346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409028102
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