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Prion protein NMR structures of elk and of mouse/elk hybrids

The NMR structure of the recombinant elk prion protein (ePrP), which represents the cellular isoform (ePrP(C)) in the healthy organism, is described here. As anticipated from the highly conserved amino acid sequence, ePrP(C) has the same global fold as other mammalian prion proteins (PrPs), with a f...

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Main Authors: Gossert, Alvar D., Bonjour, Sophie, Lysek, Dominikus A., Fiorito, Francesco, Wüthrich, Kurt
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC545551/
https://ncbi.nlm.nih.gov/pubmed/15647363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409008102
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