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Maximizing the natriuretic effect of endogenous atriopeptin in a rat model of heart failure.

The effect of pharmacological manipulation of atriopeptin (AP) activity on sodium excretion and blood pressure was examined in the rat aortovenocaval (A-V) fistula model of cardiac failure. Introduction of an A-V shunt led to a marked and sustained elevation of plasma AP immunoreactivity and urinary...

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Autori principali: Wilkins, M R, Settle, S L, Stockmann, P T, Needleman, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC54555/
https://ncbi.nlm.nih.gov/pubmed/2166956
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