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Fibrin Hydrogel Based Bone Substitute Tethered with BMP-2 and BMP-2/7 Heterodimers

Current clinically used delivery methods for bone morphogenetic proteins (BMPs) are collagen based and require large concentrations that can lead to dangerous side effects. Fibrin hydrogels can serve as osteoinductive bone substitute materials in non-load bearing bone defects in combination with BMP...

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Publicat a:Materials (Basel)
Autors principals: Karfeld-Sulzer, Lindsay S., Siegenthaler, Barbara, Ghayor, Chafik, Weber, Franz E.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455435/
https://ncbi.nlm.nih.gov/pubmed/28787983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma8030977
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