Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

PURPOSE: At least 94 common single nucleotide polymorphisms (SNPs) are associated with breast cancer. The extent to which an SNP panel can refine risk in women who receive preventive therapy has not been directly assessed previously. MATERIALS AND METHODS: A risk score on the basis of 88 SNPs (SNP88...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Cuzick, Jack, Brentnall, Adam R., Segal, Corrinne, Byers, Helen, Reuter, Caroline, Detre, Simone, Lopez-Knowles, Elena, Sestak, Ivana, Howell, Anthony, Powles, Trevor J., Newman, William G., Dowsett, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455424/
https://ncbi.nlm.nih.gov/pubmed/28029312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.69.8944
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