Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

PURPOSE: At least 94 common single nucleotide polymorphisms (SNPs) are associated with breast cancer. The extent to which an SNP panel can refine risk in women who receive preventive therapy has not been directly assessed previously. MATERIALS AND METHODS: A risk score on the basis of 88 SNPs (SNP88...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Clin Oncol
मुख्य लेखकों: Cuzick, Jack, Brentnall, Adam R., Segal, Corrinne, Byers, Helen, Reuter, Caroline, Detre, Simone, Lopez-Knowles, Elena, Sestak, Ivana, Howell, Anthony, Powles, Trevor J., Newman, William G., Dowsett, Mitchell
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Clinical Oncology 2017
विषय:
ORIGINAL REPORTS
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455424/
https://ncbi.nlm.nih.gov/pubmed/28029312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.69.8944
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