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Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin

The cholesterol-dependent cytolysins (CDCs), a superfamily of pore-forming toxins, are characterized by a conserved undecapeptide motif that is believed to be critical for membrane recognition by means of cholesterol. Intermedilysin (ILY), an unusual member of the CDCs, exhibits specificity for huma...

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Autori principali: Polekhina, Galina, Giddings, Kara Sue, Tweten, Rodney K., Parker, Michael W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC545513/
https://ncbi.nlm.nih.gov/pubmed/15637162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403229101
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