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Structures of Perfringolysin O Suggest a Pathway for Activation of Cholesterol-dependent Cytolysins
Cholesterol-dependent cytolysins (CDCs), a large family of bacterial toxins, are secreted as water-soluble monomers and yet are capable of generating oligomeric pores in membranes. Previous work has demonstrated that large scale structural rearrangements occur during this transition but the detailed...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674820/ https://ncbi.nlm.nih.gov/pubmed/17328912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.042 |
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