Toll-Like Receptor 4–Independent Carbon Tetrachloride–Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells

Gram-negative bacterial endotoxin lipopolysaccharide (LPS) is implicated in acute and chronic liver injury; its effects are mediated predominantly via the membrane receptor Toll-like receptor 4 (TLR4). However, TLR4-independent effects of LPS may play important role in hepatic pathophysiology. We in...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Kumar, Sudhir, Wang, Jiang, Shanmukhappa, Shiva Kumar, Gandhi, Chandrashekhar R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455062/
https://ncbi.nlm.nih.gov/pubmed/28412299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.01.021
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