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Assembly of Hepatocyte Spheroids Using Magnetic 3D Cell Culture for CYP450 Inhibition/Induction

There is a significant need for in vitro methods to study drug-induced liver injury that are rapid, reproducible, and scalable for existing high-throughput systems. However, traditional monolayer and suspension cultures of hepatocytes are difficult to handle and risk the loss of phenotype. Generally...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Desai, Pujan K., Tseng, Hubert, Souza, Glauco R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454994/
https://ncbi.nlm.nih.gov/pubmed/28524079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051085
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