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Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies
Human upcyte® hepatocytes are proliferating hepatocytes that retain many characteristics of primary human hepatocytes. We conducted a comprehensive evaluation of the application of second-generation upcyte® hepatocytes from four donors for inhibition and induction assays using a selection of referen...
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| Publicado no: | Pharmacol Res Perspect |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618636/ https://ncbi.nlm.nih.gov/pubmed/26516577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.161 |
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