In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells

In this study we used differentiated adult human upcyte(®) cells for the in vitro generation of liver organoids. Upcyte(®) cells are genetically engineered cell strains derived from primary human cells by lenti-viral transduction of genes or gene combinations inducing transient proliferation capacit...

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Udgivet i:PLoS One
Main Authors: Ramachandran, Sarada Devi, Schirmer, Katharina, Münst, Bernhard, Heinz, Stefan, Ghafoory, Shahrouz, Wölfl, Stefan, Simon-Keller, Katja, Marx, Alexander, Øie, Cristina Ionica, Ebert, Matthias P., Walles, Heike, Braspenning, Joris, Breitkopf-Heinlein, Katja
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619350/
https://ncbi.nlm.nih.gov/pubmed/26488607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139345
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