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Inflammation Downregulates UCP1 Expression in Brown Adipocytes Potentially via SIRT1 and DBC1 Interaction

Brown adipose tissue thermogenesis at the cost of energy is not only important for the development of obesity, but also possesses great promise in anti-obesity treatment. Uncoupling protein 1 (UCP1) expression has been reported to be under control of the intracellular deacetylase SIRT1. Here, we inv...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Nøhr, Mark K., Bobba, Natalia, Richelsen, Bjørn, Lund, Sten, Pedersen, Steen B.
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454919/
https://ncbi.nlm.nih.gov/pubmed/28481291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051006
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