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Inflammation Downregulates UCP1 Expression in Brown Adipocytes Potentially via SIRT1 and DBC1 Interaction

Brown adipose tissue thermogenesis at the cost of energy is not only important for the development of obesity, but also possesses great promise in anti-obesity treatment. Uncoupling protein 1 (UCP1) expression has been reported to be under control of the intracellular deacetylase SIRT1. Here, we inv...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Nøhr, Mark K., Bobba, Natalia, Richelsen, Bjørn, Lund, Sten, Pedersen, Steen B.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454919/
https://ncbi.nlm.nih.gov/pubmed/28481291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051006
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