Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome

Our genomes are subject to potentially deleterious alterations resulting from endogenous sources (e.g., cellular metabolism, routine errors in DNA replication and recombination), exogenous sources (e.g., radiation, chemical agents), and medical diagnostic and treatment applications. Genome integrity...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Mirzayans, Razmik, Andrais, Bonnie, Kumar, Piyush, Murray, David
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454841/
https://ncbi.nlm.nih.gov/pubmed/28452953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050928
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