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Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome

Our genomes are subject to potentially deleterious alterations resulting from endogenous sources (e.g., cellular metabolism, routine errors in DNA replication and recombination), exogenous sources (e.g., radiation, chemical agents), and medical diagnostic and treatment applications. Genome integrity...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mirzayans, Razmik, Andrais, Bonnie, Kumar, Piyush, Murray, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454841/
https://ncbi.nlm.nih.gov/pubmed/28452953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050928
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