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Redesign of a WW Domain Peptide for Selective Recognition of ssDNA
A β-sheet mini-protein based on the FBP11 WW1 domain sequence has been redesigned for the molecular recognition of ssDNA. A previous report showed that a β-hairpin peptide dimer, (WKWK)(2), binds ssDNA with low micromolar affinity but with little selectivity over duplex DNA. This report extends thos...
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| Vydáno v: | Biochemistry |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454779/ https://ncbi.nlm.nih.gov/pubmed/21332166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101116a |
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