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Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway

Rad23 protein interacts with the nucleotide excision-repair (NER) factor Rad4, and the dimer can bind damaged DNA. Rad23 also binds ubiquitinated proteins and promotes their degradation by the proteasome. Rad23/proteasome interaction is required for efficient NER, although the specific role of the U...

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Autori principali: Ortolan, Tatiana G., Chen, Li, Tongaonkar, Prasad, Madura, Kiran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC545455/
https://ncbi.nlm.nih.gov/pubmed/15601997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh987
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