A FKBP5 mutation is associated with Paget's disease of bone and enhances osteoclastogenesis

Paget's disease of bone (PDB) is a common metabolic bone disease that is characterized by aberrant focal bone remodeling, which is caused by excessive osteoclastic bone resorption followed by disorganized osteoblastic bone formation. Genetic factors are a critical determinant of PDB pathogenesi...

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Dettagli Bibliografici
Pubblicato in:Exp Mol Med
Autori principali: Lu, Bingru, Jiao, Yulian, Wang, Yinchang, Dong, Jing, Wei, Muyun, Cui, Bin, Sun, Yafang, Wang, Laicheng, Zhang, Bingchang, Chen, Zijiang, Zhao, Yueran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454451/
https://ncbi.nlm.nih.gov/pubmed/28524179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.64
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