Selective BET bromodomain inhibition as an antifungal therapeutic strategy

Invasive fungal infections cause significant morbidity and mortality among immunocompromised individuals, posing an urgent need for new antifungal therapeutic strategies. Here we investigate a chromatin-interacting module, the bromodomain (BD) from the BET family of proteins, as a potential antifung...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Mietton, Flore, Ferri, Elena, Champleboux, Morgane, Zala, Ninon, Maubon, Danièle, Zhou, Yingsheng, Harbut, Mike, Spittler, Didier, Garnaud, Cécile, Courçon, Marie, Chauvel, Murielle, d'Enfert, Christophe, Kashemirov, Boris A., Hull, Mitchell, Cornet, Muriel, McKenna, Charles E., Govin, Jérôme, Petosa, Carlo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454392/
https://ncbi.nlm.nih.gov/pubmed/28516956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15482
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