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Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin

In the cerebellar cortex, Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and serve as an integration centre. Defects in the dendritic development of PCs thus disrupt cerebellar circuitry and cause ataxia. Here we report that specific inactivat...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lui, Nga Chu, Tam, Wing Yip, Gao, Caiji, Huang, Jian-Dong, Wang, Chi Chiu, Jiang, Liwen, Yung, Wing Ho, Kwan, Kin Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454373/
https://ncbi.nlm.nih.gov/pubmed/28516904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15079
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