The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice

Obesity causes excess fat accumulation in white adipose tissues (WAT) and also in other insulin-responsive organs such as the skeletal muscle, increasing the risk for insulin resistance, which can lead to obesity-related metabolic disorders. Peroxisome proliferator-activated receptor-α (PPARα) is a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Goto, Tsuyoshi, Hirata, Mariko, Aoki, Yumeko, Iwase, Mari, Takahashi, Haruya, Kim, Minji, Li, Yongjia, Jheng, Huei-Fen, Nomura, Wataru, Takahashi, Nobuyuki, Kim, Chu-Sook, Yu, Rina, Seno, Shigeto, Matsuda, Hideo, Aizawa-Abe, Megumi, Ebihara, Ken, Itoh, Nobuyuki, Kawada, Teruo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454100/
https://ncbi.nlm.nih.gov/pubmed/28404815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767590
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