The dipeptidyl peptidase‐4 (DPP‐4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice

To clarify the effects of a dipeptidyl peptidase‐4 (DPP‐4) inhibitor on whole‐body energy metabolism, we treated mice fed a high‐fat diet (HFD) with teneligliptin, a clinically available DPP‐4 inhibitor. Teneligliptin significantly prevented HFD‐induced obesity and obesity‐associated metabolic disor...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Takeda, Kenichiro, Sawazaki, Honami, Takahashi, Haruya, Yeh, Yu‐Sheng, Jheng, Huei‐Fen, Nomura, Wataru, Ara, Takeshi, Takahashi, Nobuyuki, Seno, Shigeto, Osato, Naoki, Matsuda, Hideo, Kawada, Teruo, Goto, Tsuyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212644/
https://ncbi.nlm.nih.gov/pubmed/30410858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12498
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