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Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?

Sphingosine 1-phosphate (S1P) is a bioactive lipid that is characterized by a peculiar mechanism of action. In fact, S1P, which is produced inside the cell, can act as an intracellular mediator, whereas after its export outside the cell, it can act as ligand of specific G-protein coupled receptors,...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Vestri, Ambra, Pierucci, Federica, Frati, Alessia, Monaco, Lucia, Meacci, Elisabetta
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454082/
https://ncbi.nlm.nih.gov/pubmed/28626422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00296
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